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- From: "Creative Diagnostics" <customer AT creativediagnositcs.com>
- To: <opal AT lists.psi.ch>
- Subject: [Opal] [PSI-IT WARNING: SUSPECTED SPAM] The Novel Mouse Immunization Adjuvant
- Date: Tue, 4 Mar 2014 08:23:51 -0500
- Bounces-to: bounce_biiimj_iahyjbz AT cp20.com
- List-archive: <https://lists.web.psi.ch/pipermail/opal/>
- List-id: The OPAL Discussion Forum <opal.lists.psi.ch>
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Magic Mouse Adjuvant is a novel immunization adjuvant specifically designed for rapid production of high titers of antibodies in mice. The adjuvant contains immune-stimulatory CpG DNA — short oligonucleotides that contain unmethylated cytosine-guanine dinucleotides within a certain base context. The mammalian immune system has evolved to recognize these sequences, which are found naturally in bacterial DNA, as a sign of infection. Exposure to CpG DNA results in very rapid and strong immune activation, and, when applied with an antigen, CpG DNA produces high titers of antigen-specific antibodies. Different CpG DNA sequences activate the immune systems of different animal species. Magic Mouse Adjuvant contains a proprietary DNA sequence that is specifically designed for immunization of mice. |
Key Features of the Adjuvant:
1.Highly effective -- rapid production of high titers of antibodies. Only 1-2 immunizations are necessary for polyclonal antibody production and 2-3 immunizations for hybridoma generation.
2.Immunogen -- and adjuvant-sparing —much less immunogen required than with conventional methods.
3.Time-saving -- strong immune responses can be reached within 12 days after first immunization or 12 days after the second immunization.
4.Extremely valuable -- in producing antibodies against conformational epitopes.
5.Safe -- non-toxic adjuvant with no adverse side effects to animals.
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Magic Mouse Adjuvant has been used in the following featured services:
Magic Mouse Adjuvant can be purchased as a standalone product.
For additional information, please ask Creative Diagnostics!
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Copyright 2009 - 2014 (c) Creative Diagnostics. All rights reserved.
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- [Opal] [PSI-IT WARNING: SUSPECTED SPAM] The Novel Mouse Immunization Adjuvant, Creative Diagnostics, 03/04/2014
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