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Single-Cell Sequencing Service

Dear Friends,

CD Genomics offers Single-Cell Sequencing which examines the sequence information from individual cells with optimized next generation sequencing (NGS) technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment.

Biological research often involves the analysis of tissues, cell populations and whole organisms. However, much variation occurs at the single-cell level where understanding of each individual cell is crucial for the analysis of the entire system. Cancer cells, for example, are heterogeneous populations of multiple clonal expansions, and analyzing a tumor as one entity could mask many important characteristics of the tumor. The ideal approach to such system biology thus requires analyzing 'parts' of these systems individually, using methods and technologies that can extract data at few or single-cell levels.

Single-Cell Sequencing Process:

Services Advantages
High throughput - Get higher efficiency with parallel sequencing preparation of 96 individual cells
Ultra sensitive - Less quantity of input DNA required
Full gene analysis - Gives better read coverage across the entire transcript for better detailed analysis of alternative transcript isoforms and identification of single nucleotide polymorphisms
High accuracy and low interference - Our service utilizes state-of-the-art technology to eliminate background interference

Single-Cell Sequencing Service Application

Medical applications of single-cell sequencing:	Profiling scarce clinical samples, such as fine-needle aspirates of breast lesions Measuring intra-tumor heterogeneity and guiding chemotherapy Cancer cells evolution analysis during tumor progression Isolation and profiling of circulating tumor cells in the blood Pre-implantation genetic diagnosis (PGD)
Other aspects of the application:	Identify microbiomes' identities and its genomes

With CD Genomics, you gain access to the latest single-cell sequencing technology on the market & get the highest consensus accuracy, professional data analysis.

If you have any questions, please feel free to contact us!

Sincerely,
Nancy Russ
CD Genomics
45-1 Ramsey Road Shirley, NY 11967 US
USA: 1-631-626-9181
UK: 44-207-048-3343
Fax: 1-631-614-7828
Email：info AT CD-Genomics.org

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