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["Creative Biostructure" <customer AT creativebiostructure-mail.com>]

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96f Well Crystallization Plate

1 Protein _expression_ and Purification:
We will work with you to determine the best protocol for your target protein _expression_. Our lab is equipped with both traditional chromatography systems and HPLC for large-scale protein purification, as well as dynamic light scattering, UV spectrometry, mass spectrometry and amino acid sequencing system for purity, activity and aggregation state tests.

2 Crystallization Screening:
We will screen more than 768 crystallization conditions for freshly purified target proteins and compounds provided by clients. If crystals are obtained, we will fine-tune the conditions to generate diffraction-grade crystals.

3 X-ray Diffraction Data Collection:
We can collect X-ray diffraction data by using both our powerful in-house X-ray generator and synchrotron X-ray sources.

XtalFinder

4 Structure Determination:
We can solve both de novo structures using multi-wavelength X-ray methods and structures based on known 3-D structure of homologs of target protein using molecular replacement method.

Protein Analysis
Platform

Mass spectrometry
Dynamic light scattering
Analytical ultracentrifugation


Protein Analysis/X-ray
Platforms

In-house Rigaku MicroMAX 007 plus R-AXIS IV++
imaging plate area detector
Access to synchrotron radiation beamlines








Address: 45-16
Ramsey Road Shirley, NY 11967,USA 
 Tel: 1-866-588-6325 | Fax:
1-631-207-8356 
 Email: Info AT creative-biostructure.org
 Website: www.creative-biostructure.org




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